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If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. It frequently affects girls and is characterized by dry eye syndrome, mouth and sometimes systemic involvement. Its diagnosis is difficult to establish in children. Anonymity and respect for ethical rules were the norm. There was no connection between the patients and the researchers.
The mean age of the patients was 11 years with extremes of 5—15 years. History reveals that a dry mouth was found in more than half of the cases, or in 10 The immunological workup and the biopsy of the accessory salivary glands served as diagnostic evidence in the 15 patients according to the US—European criteria of Its diagnosis is difficult to establish in pediatrics and its severity is linked to the occurrence of late visceral and lymphomatous sicca syndrome.
Rapid diagnosis and initiation of a synthetic antimalarial hydroxychloroquine increases the hope of a cure. It affects girls much more than boys [ 3 ] and is characterized by dry eye and mouth syndrome and in almost a third of patients the pathology is more systemic and can affect various organs [ 4 ]. Diagnosis is difficult in children given their inability to list their symptoms accurately and the difficulty in obtaining reliable data on the personal and family history of children.
Diagnosis is based on a combination of clinical biological and immunological signs and biopsy of the accessory salivary glands [ 5 , 6 , 7 ].
